ALMA BEATRIZ PEREGRINO URIARTE
M.C. Alma Beatriz Peregrino Uriarte

Profesora Investigadora Asociada C

SNI I

Líneas de investigación: Metabolismo energético central, alteraciones en expresión y actividad enzimática en respuesta a hipoxia; Sistema antioxidante y respuestas a estresores ambientales; Efectos de contaminantes tóxicos en organismos acuáticos.

Metabolismo energético Antioxidantes Estrés oxidativo Camarón Hipoxia

Google AcadémicoResearchGate

Coordinación

Tecnología de Alimentos de Origen Animal

Teléfono

+52 (662) 289 2400, ext. 614

Correo electrónico

almabper@ciad.mx

Maestría: Nutrición y Ciencias,CIAD, 1996.

Licenciatura: Química Bióloga esp. Tecnología de Alimentos, Unison, 1991.

  • Respuestas metabólicas y de sistemas antioxidantes ante el estrés ambiental y por contaminantes en crustáceos marinos.
  • Estrada Cardenas P., Peregrino Uriarte A.B., *Yepiz Plascencia G.M. 2023. Glutathione peroxidase 4 knock-down triggers ferroptosis in Penaeus vannamei hepatopancreas during hypoxia and reoxygenation. Fish and Shellfish Immunology 143:109201.
    https://doi.org/10.1016/j.fsi.2023.109201
  • Estrada Cardenas P., Peregrino Uriarte A.B., Gómez Jiménez S., Valenzuela Soto E.M., Leyva Carrillo L., *Yepiz Plascencia G.M. 2023. Responses and modulation of the white shrimp Litopenaeus vannamei glutathione peroxidases 2 and 4 during hypoxia, reoxygenation and GPx4 knock-down. Biochimie214:157-164. https://doi.org/10.1016/j.biochi.2023.07.006
  • Camacho Jiménez L., Peregrino Uriarte A.B., Leyva Carrillo L., Gómez Jiménez S., Thies A., Tresguerres M., *Yepiz Plascencia G.M. 2023. Effects of severe hypoxia and glyceraldehyde-3- phosphate dehydrogenase (GAPDH) knock- down on its gene expression, activity, subcellular localization, and apoptosis in gills of the shrimp Penaeus vannamei. Marine and Freshwater Behaviour and Physiology. 56(3–4):91–110 https://doi.org/10.1080/10236244.2023.2216346
  • Cruz-Moreno P., Valenzuela_Soto E, Peregrino-Uriarte A.B., Leyva-Carrillo L., Soñanez-Organis J.G., Yepiz-Plascencia G. 2023. The pyruvate kinase of the whiteleg shrimp Litopenaeus vannamei: Gene structure and responses to short term hypoxia. Comp Biochem Physiol A Mol Integr Physiol. 283: 111468
  • Hernández-Aguirre L.E., Peregrino-Uriarte A-B., Duarte Gutiérrez J.L., Leyva-Carrillo L., Ezquerra-Brauer J.M., Valenzuela-Soto E.M., Yepiz-Plascencia G. 2023. Shrimp Glucose-6-Phpshatase 2 (G6Pase 2): a second isoform of G6Pase in the Pacific white shrimp and regulation of G6Pase 1 and 2 isoforms via HIF-1 during hypoxia and reoxygenation in juveniles. Journal of Bioenergetics and Biomembranes https://doi.org/10.1007/s10863-023-09960-z
  • Granillo-Luna ON, Hernández-Aguirre LE, Peregrino-Uriarte AB, Duarte-Gutiérrez J, Contreras-Vergara CA, Gollas-Galvan T, Yepiz-Plascencia G. 2022. The anaplerotic pyruvate carboxylase from white shrimp Litopenaeus vannamei: Gene structure, molecular characterization, protein modelling and expression during hypoxia. Comp Biochem Physiol A Mol Integr Physiol. 11;269:111212. doi: 10.1016/j.cbpa.2022.111212
  • Estrada-Cárdenas P, Camacho-Jiménez L, Peregrino-Uriarte AB, Contreras-Vergara CA, Hernandez-López J, Yepiz-Plascencia G. 2022. p53 knock-down and hypoxia affects glutathione peroxidase 4 antioxidant response in hepatopancreas of the white shrimp Litopenaeus vannamei. Biochimie. 1;199:1-11. doi: 10.1016/j.biochi.2022.03.010.
  • González-Ruiz R, Leyva-Carrillo L, Peregrino-Uriarte AB, Yepiz-Plascencia G. 2022. The combination of hypoxia and high temperature affects heat shock, anaerobic metabolism, and pentose phosphate pathway key components responses in the white shrimp (Litopenaeus vannamei). Cell Stress Chaperones. doi: 10.1007/s12192-022-01265-1.
  • Flores-Sauceda M., Camacho-Jiménez L., Peregrino-Uriarte A.B., Leyva-Carrillo L., Arvizu-Flores A, Yepiz-Plascencia G. 2022. The bifunctional 6-phosphofructokinase-2/frustose-2,6-bisphoshatase from the shrimp Litopenaus vannamei: Molecualr characterization and down-regulation of expression in response to severe hypoxia. Comparative Biochemistry and Physiology, Part A. 263: 111095 https://doi.org/10.1016/j.cbpa.2021.111095
  • Duarte-Gutiérrez J., Peregrino-Uriarte A.B., Gómez-Jiménez S., Mata-Haro V., Yepiz-Plascencia G. 2021. HIF-1 is involved in the regulation of expression of metallothionein and apoptosis incidence in the white shrimp Litopenaeus vannamei. Comparative Biochemistry and Physiology, Part A. 262, Article number 111072, DOI 10.1016/j.cbpa.2021.111072
  • Hernández-Aguirre L., Cota-Ruiz K., Peregrino-Uriate A.B., Gómez-Jiménez S., Yepiz-Plascencia G. 2021. The gluconeogenic glucosa 6-phosphatase gene is expressed durong oxygen-limited conditions in the white shrimp Litpenaeus vannamei: Molecular cloning, membrane protein modeling and transcript modulation in gills and hepatopncreas. Journal of Bioenegetics and Biomembranes. 53: 449-461 https://doi.org/10.1007/s10863-021-09903-6
  • Nuñez-Hernández D., Camacho-Jimenéz L., Leyva-Carrillo L., Peregrino-Uriarte A.B., Valenzuela-Soto E.M., Gómez-Jiménez S., Gonzalez-Rios H., Yepiz- Plascencia G. 2021. Expression of p53 isoforms in response to two levels of hipoxia and effects of p53 knock-down in glyceraldehyde-3-phpsphate dehydrogenase in the white shrimp Litopenaesus vannamei. Aquaculture Research. 00:1-11. DOI: 10.1111/are.15083
  • Estrada-Cárdenas P., Cruz-Moreno D., González-Ruiz R., Peregrino-Uriarte A., Leyva-Carrillo L., Camacho-Jiménez L., Quintero-Reyes I., Yepiz-Plascencia G. 2021. Combined hipoxia and high temperature affect differentially the response of antioxidant enzymes, glutathione and hydrogen peroxide in the White shrimp Litopenaeus vannamei. Comparative Biochemistry and Physiology, Part A. 254: 110909. doi.org/10.1016/j.cbpa.2021.110909
  • González-Ruiz R., Peregrino-Uriarte A.B., Valenzuela-Soto E.M., Cinco-Moroyoqui F.J., Martínez-Tellez M.A., Yepiz-Plascencia G. 2021. Mitochondrial manganese superoxide dismutase knock-down increases oxidative stress and caspase-3 activity in the White shrimp Litopenaeus vannamei exposed to high temperatura, hipoxia, and reoxygenation. Comparative Biochemistry and Physiology, Part A. 253: 110826. DOI https://doi.org/10.1016/j.cbpa.2020.110826
  • Gonzalez-Ruiz R., Granillo-Luna O., Peregrino-Uriarte A.B., Gomez-Jimenez S., Yepiz-Plascencia G. 2020. Mitochondrial manganese superoxide dismutase from the shrimp Litopenaeus vannamei: Molecular characterization and effect of high temperature, hypoxia and reoxygenation on expression and enzyme activity. Journal of Thermal Biology. 88: 102519 https://doi.org/10.1016/j.jtherbio.2020.102519
  • Tesis de maestría en ciencias de Marissa Andrea Flores Sauceda. Caracterización Molecular de las isoformas de la hexocinasa del camarón blanco Litopenaeus vannamei y su expresión génica en hipoxia y reoxigenación. Posgrado CIAD. 2022.
  • Tesis de maestría en ciencias de Dalia Cruz Moreno. Efecto del estrés por hipoxia, reoxigenación y temperatura alta en la concentración de peróxido de hidrógeno, actividad y expresión de catalasa en Litopenaeus vannamei. Posgrado CIAD. 2019.
  • Tesis de licenciatura de Omar Noé Granillo Luna. La superóxico dismutasa mitocondrial de manganeso del camarón blanco Litopenaeus vannamei (Boone, 1931): Caracterización molecular y expresión. Universidad de Sonora. Junio, 2018.
  • Tesis de licenciatura de Dulce María Caraveo Gutiérrez. Caracterización del gen de trehalosa fosfato sintasa del camarón blanco Litopenaeus vannamei. Instituto Tecnológico de Sonora. Febrero, 2016.
  • Tesis de maestría en ciencias de Ambar Azeneth Fregoso Peñuñuri. Caracterización bioquímica y cinética de la lactato deshidrogenasa 2 (LDH-2) recombinante de camarón blanco Litopenaeus vannamei. Posgrado CIAD. 2015.
Formación profesional

Maestría: Nutrición y Ciencias,CIAD, 1996.

Licenciatura: Química Bióloga esp. Tecnología de Alimentos, Unison, 1991.

Áreas de Interés
  • Respuestas metabólicas y de sistemas antioxidantes ante el estrés ambiental y por contaminantes en crustáceos marinos.
Publicaciones seleccionadas
  • Estrada Cardenas P., Peregrino Uriarte A.B., *Yepiz Plascencia G.M. 2023. Glutathione peroxidase 4 knock-down triggers ferroptosis in Penaeus vannamei hepatopancreas during hypoxia and reoxygenation. Fish and Shellfish Immunology 143:109201.
    https://doi.org/10.1016/j.fsi.2023.109201
  • Estrada Cardenas P., Peregrino Uriarte A.B., Gómez Jiménez S., Valenzuela Soto E.M., Leyva Carrillo L., *Yepiz Plascencia G.M. 2023. Responses and modulation of the white shrimp Litopenaeus vannamei glutathione peroxidases 2 and 4 during hypoxia, reoxygenation and GPx4 knock-down. Biochimie214:157-164. https://doi.org/10.1016/j.biochi.2023.07.006
  • Camacho Jiménez L., Peregrino Uriarte A.B., Leyva Carrillo L., Gómez Jiménez S., Thies A., Tresguerres M., *Yepiz Plascencia G.M. 2023. Effects of severe hypoxia and glyceraldehyde-3- phosphate dehydrogenase (GAPDH) knock- down on its gene expression, activity, subcellular localization, and apoptosis in gills of the shrimp Penaeus vannamei. Marine and Freshwater Behaviour and Physiology. 56(3–4):91–110 https://doi.org/10.1080/10236244.2023.2216346
  • Cruz-Moreno P., Valenzuela_Soto E, Peregrino-Uriarte A.B., Leyva-Carrillo L., Soñanez-Organis J.G., Yepiz-Plascencia G. 2023. The pyruvate kinase of the whiteleg shrimp Litopenaeus vannamei: Gene structure and responses to short term hypoxia. Comp Biochem Physiol A Mol Integr Physiol. 283: 111468
  • Hernández-Aguirre L.E., Peregrino-Uriarte A-B., Duarte Gutiérrez J.L., Leyva-Carrillo L., Ezquerra-Brauer J.M., Valenzuela-Soto E.M., Yepiz-Plascencia G. 2023. Shrimp Glucose-6-Phpshatase 2 (G6Pase 2): a second isoform of G6Pase in the Pacific white shrimp and regulation of G6Pase 1 and 2 isoforms via HIF-1 during hypoxia and reoxygenation in juveniles. Journal of Bioenergetics and Biomembranes https://doi.org/10.1007/s10863-023-09960-z
  • Granillo-Luna ON, Hernández-Aguirre LE, Peregrino-Uriarte AB, Duarte-Gutiérrez J, Contreras-Vergara CA, Gollas-Galvan T, Yepiz-Plascencia G. 2022. The anaplerotic pyruvate carboxylase from white shrimp Litopenaeus vannamei: Gene structure, molecular characterization, protein modelling and expression during hypoxia. Comp Biochem Physiol A Mol Integr Physiol. 11;269:111212. doi: 10.1016/j.cbpa.2022.111212
  • Estrada-Cárdenas P, Camacho-Jiménez L, Peregrino-Uriarte AB, Contreras-Vergara CA, Hernandez-López J, Yepiz-Plascencia G. 2022. p53 knock-down and hypoxia affects glutathione peroxidase 4 antioxidant response in hepatopancreas of the white shrimp Litopenaeus vannamei. Biochimie. 1;199:1-11. doi: 10.1016/j.biochi.2022.03.010.
  • González-Ruiz R, Leyva-Carrillo L, Peregrino-Uriarte AB, Yepiz-Plascencia G. 2022. The combination of hypoxia and high temperature affects heat shock, anaerobic metabolism, and pentose phosphate pathway key components responses in the white shrimp (Litopenaeus vannamei). Cell Stress Chaperones. doi: 10.1007/s12192-022-01265-1.
  • Flores-Sauceda M., Camacho-Jiménez L., Peregrino-Uriarte A.B., Leyva-Carrillo L., Arvizu-Flores A, Yepiz-Plascencia G. 2022. The bifunctional 6-phosphofructokinase-2/frustose-2,6-bisphoshatase from the shrimp Litopenaus vannamei: Molecualr characterization and down-regulation of expression in response to severe hypoxia. Comparative Biochemistry and Physiology, Part A. 263: 111095 https://doi.org/10.1016/j.cbpa.2021.111095
  • Duarte-Gutiérrez J., Peregrino-Uriarte A.B., Gómez-Jiménez S., Mata-Haro V., Yepiz-Plascencia G. 2021. HIF-1 is involved in the regulation of expression of metallothionein and apoptosis incidence in the white shrimp Litopenaeus vannamei. Comparative Biochemistry and Physiology, Part A. 262, Article number 111072, DOI 10.1016/j.cbpa.2021.111072
  • Hernández-Aguirre L., Cota-Ruiz K., Peregrino-Uriate A.B., Gómez-Jiménez S., Yepiz-Plascencia G. 2021. The gluconeogenic glucosa 6-phosphatase gene is expressed durong oxygen-limited conditions in the white shrimp Litpenaeus vannamei: Molecular cloning, membrane protein modeling and transcript modulation in gills and hepatopncreas. Journal of Bioenegetics and Biomembranes. 53: 449-461 https://doi.org/10.1007/s10863-021-09903-6
  • Nuñez-Hernández D., Camacho-Jimenéz L., Leyva-Carrillo L., Peregrino-Uriarte A.B., Valenzuela-Soto E.M., Gómez-Jiménez S., Gonzalez-Rios H., Yepiz- Plascencia G. 2021. Expression of p53 isoforms in response to two levels of hipoxia and effects of p53 knock-down in glyceraldehyde-3-phpsphate dehydrogenase in the white shrimp Litopenaesus vannamei. Aquaculture Research. 00:1-11. DOI: 10.1111/are.15083
  • Estrada-Cárdenas P., Cruz-Moreno D., González-Ruiz R., Peregrino-Uriarte A., Leyva-Carrillo L., Camacho-Jiménez L., Quintero-Reyes I., Yepiz-Plascencia G. 2021. Combined hipoxia and high temperature affect differentially the response of antioxidant enzymes, glutathione and hydrogen peroxide in the White shrimp Litopenaeus vannamei. Comparative Biochemistry and Physiology, Part A. 254: 110909. doi.org/10.1016/j.cbpa.2021.110909
  • González-Ruiz R., Peregrino-Uriarte A.B., Valenzuela-Soto E.M., Cinco-Moroyoqui F.J., Martínez-Tellez M.A., Yepiz-Plascencia G. 2021. Mitochondrial manganese superoxide dismutase knock-down increases oxidative stress and caspase-3 activity in the White shrimp Litopenaeus vannamei exposed to high temperatura, hipoxia, and reoxygenation. Comparative Biochemistry and Physiology, Part A. 253: 110826. DOI https://doi.org/10.1016/j.cbpa.2020.110826
  • Gonzalez-Ruiz R., Granillo-Luna O., Peregrino-Uriarte A.B., Gomez-Jimenez S., Yepiz-Plascencia G. 2020. Mitochondrial manganese superoxide dismutase from the shrimp Litopenaeus vannamei: Molecular characterization and effect of high temperature, hypoxia and reoxygenation on expression and enzyme activity. Journal of Thermal Biology. 88: 102519 https://doi.org/10.1016/j.jtherbio.2020.102519
Dirección de tesis
  • Tesis de maestría en ciencias de Marissa Andrea Flores Sauceda. Caracterización Molecular de las isoformas de la hexocinasa del camarón blanco Litopenaeus vannamei y su expresión génica en hipoxia y reoxigenación. Posgrado CIAD. 2022.
  • Tesis de maestría en ciencias de Dalia Cruz Moreno. Efecto del estrés por hipoxia, reoxigenación y temperatura alta en la concentración de peróxido de hidrógeno, actividad y expresión de catalasa en Litopenaeus vannamei. Posgrado CIAD. 2019.
  • Tesis de licenciatura de Omar Noé Granillo Luna. La superóxico dismutasa mitocondrial de manganeso del camarón blanco Litopenaeus vannamei (Boone, 1931): Caracterización molecular y expresión. Universidad de Sonora. Junio, 2018.
  • Tesis de licenciatura de Dulce María Caraveo Gutiérrez. Caracterización del gen de trehalosa fosfato sintasa del camarón blanco Litopenaeus vannamei. Instituto Tecnológico de Sonora. Febrero, 2016.
  • Tesis de maestría en ciencias de Ambar Azeneth Fregoso Peñuñuri. Caracterización bioquímica y cinética de la lactato deshidrogenasa 2 (LDH-2) recombinante de camarón blanco Litopenaeus vannamei. Posgrado CIAD. 2015.
Grupos de investigación
Laboratorios

Laboratorio de Biología Molecular y Bioquímica

Líneas de Generación y Aplicación del Conocimiento
  • Biotecnología de Organismos Acuáticos
  • Biología Molecular.